Contraindicated. CYP3A4 is chargeable for the development and elimination of cariprazine's active metabolites. The result of CYP3A4 inducers on cariprazine exposure hasn't been evaluated and the Internet impact is unclear.pentobarbital decreases levels of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent
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